Complex regulation controls Neurogenin3 proteolysis
نویسندگان
چکیده
منابع مشابه
Complex regulation controls Neurogenin3 proteolysis
The ubiquitin proteasome system (UPS) is known to be responsible for the rapid turnover of many transcription factors, where half-life is held to be critical for regulation of transcriptional activity. However, the stability of key transcriptional regulators of development is often very poorly characterised. Neurogenin 3 (Ngn3) is a basic helix-loop-helix transcription factor that plays a centr...
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ژورنال
عنوان ژورنال: Biology Open
سال: 2012
ISSN: 2046-6390
DOI: 10.1242/bio.20121750